Research on the Mineral Boron
The following articles are presented as a reflection for
the use of ionic minerals boron as a dietary supplement and nutritional supplement. You
will find more on boron here. You can also
purchase this diet supplement below.
GENERAL BORON RESEARCH
Nielsen, F. H. (1994) Environ Health Perspect, 102(Suppl
7), 59-63.
Boron deprivation experiments with humans have yielded some
persuasive findings for the hypothesis that boron is an
essential nutrient. In the first nutritional study with humans involving boron, 12 postmenopausal women first were fed a diet that provided
0.25 mg boron/2000 kcal for 119 days, and then were fed the
same diet with a boron supplement of 3 mg boron/day for 48 days. The boron
supplementation reduced the total plasma concentration of calcium and the urinary
excretions of calcium and magnesium, and elevated the serum concentrations of 17
beta-estradiol and testosterone. This study was followed by one in which five men over the
age of 45, four postmenopausal women, and five postmenopausal women on estrogen therapy
were fed a boron-low diet (0.23 mg/2000 kcal) for 63 days,
then fed the same diet supplemented with 3 mg boron/day for
49 days. The diet was low in magnesium (115 mg/2000 kcal) and marginally adequate in
copper (1.6 mg/2000 kcal) throughout the study. This experiment found higher erythrocyte
superoxide dismutase, serum enzymatic ceruloplasmin, and plasma copper during boron repletion than boron depletion.
The design of the most recent experiment was the same as the second study, except this
time the diet was adequate in magnesium and copper. Estrogen therapy increased plasma
copper and serum 17 beta-estradiol concentrations; the increases were depressed by boron deprivation. Estrogen ingestion also increased serum
immunoreactive ceruloplasmin and erythrocyte superoxide dismutase; these variables also
were higher during boron repletion than depletion for all
subjects, not just those ingesting estrogen.(ABSTRACT TRUNCATED AT 250 WORDS).
Bone Density/ Physiology/ Boron/ Administration & Dosage/ *Deficiency/ Physiology/
Calcium/ *Blood/ Copper/ Blood/ Dose-Response Relationship, Drug/ Estradiol/ *Blood/
Estrogen Replacement Therapy/ Female/ Human/ Magnesium/ *Blood/ Male/ Middle Age/
Nutritional Requirements/ Testosterone/ *Blood.
Nielsen, F. H. (1991) F-A-S-E-B-J-Off-Publ-Fed-Am-Soc-Exp-Biol,
5(12), 2661-2667.
Definition of specific biochemical functions in higher
animals (including humans) for the ultra trace elements boron,
silicon, vanadium, nickel, and arsenic still has not been achieved although all of these
elements have been described as being essential nutrients. Recently, many new findings
from studies using molecular biology techniques, sophisticated equipment, unusual
organisms, and newly defined enzymes have revealed possible sites of essential action for
these five elements. Based on these findings and the response of animals and/or humans to
low intakes of these elements, the following speculations have been presented: 1)Boron has a role that affects cell membrane characteristics and
transmembrane signaling. 2)Silicon is necessary for the association between cells and one
or more macromolecules such as osteonectin, which affects cartilage composition and
ultimately cartilage calcification. 3)Vanadium reacts with hydrogen peroxide to form a
pervanadate that is required to catalyze the oxidation of halide ions and/or stimulate the
phosphorylation of receptor proteins. 4)Nickel is needed for the C02-fixation to
propionyl-CoA to form D-methylmalonyl-CoA. 5)Arsenic has an important role in the
conversion of methionine to its metabolites taurine, labile methyl, and the polyamines. If
any of these speculations are found to be true, the element involved will be firmly
established as having a nutritional requirement because the body obviously cannot
synthesize it. Based on animal findings, the dietary requirement is likely to be small;
that is, expressed in micrograms per day.
DNAL QH301.F3.
human-nutrition-research/ arsenic-/ boron-/ nickel-/ silicon-/ vanadium-/
nutrient-requirements/ literature-reviews.
Hunt, C. D., Shuler, T. R., & Mullen, L. M. (1991) J
Am Diet Assoc, 91(5), 558-568.
The element boron is
ubiquitous in the environment. Comparatively low concentrations of dietary boron affect several aspects of mineral metabolism in animals and
human beings. Therefore, it is appropriate to determine precisely the concentration of boron in human foodstuffs and absorbed, inhaled, or ingested
nonfood substances. In this article, we report the analyzed concentrations of boron and other elements in selected foods (animal products, water,
condiments, confections, fruits, tuberized roots, vegetables, cereal grains, and spices)
and personal-care products (analgesics, antibiotics, decongestants, antihistamines, dental
hygiene products, gastric antacids, and laxatives). We conclude tat daily intake of boron usually differs considerably between any two individuals for
three main reasons. First, concentration of boron in water
varies considerably according to geographic source. At some locations, boron in drinking water and water based beverages may account for
most of the total dietary boron intake. Second, individual
food preference greatly influences daily intake of boron.
Fruits, vegetables, tubers, and legumes have relatively much higher concentrations of boron than do cereal grains or animal tissues and fluids. Third, boron was determined to be a notable contaminant or major
ingredient of many personal care products.
DNAL-FNC 389.8-AM34.
foods-/ boron-/ nutrient-intake/ cosmetics-/ drugs-/ drinking-water/ food-preferences/
non-food-products/ mineral-content.
Nielsen, F. H., Hunt, C. D., Mullen, L. M., & Hunt, J.
R. (1987) FASEB J, 1(5), 394-7.
A study was done to examine the effects of aluminum,
magnesium, and boron on major mineral metabolism in
postmenopausal women. This communication describes some of the effects of dietary boron on 12 women between the ages of 48 and 82 housed in a
metabolic unit. A boron supplement of 3 mg/day markedly
affected several indices of mineral metabolism of seven women consuming a low-magnesium
diet and five women consuming a diet adequate in magnesium; the women had consumed a
conventional diet supplying about 0.25 mg boron/day for 119
days. Boron supplementation markedly reduced the urinary
excretion of calcium and magnesium; the depression seemed more marked when dietary
magnesium was low. Boron supplementation depressed the
urinary excretion of phosphorus by the low-magnesium, but not by the adequate-magnesium,
women. Boron supplementation markedly elevated the serum
concentrations of 17 beta-estradiol and testosterone; the elevation seemed more marked
when dietary magnesium was low. Neither high dietary aluminum (1000 mg/day) nor an
interaction between boron and aluminum affected the variables
presented. The findings suggest that supplementation of a low-boron
diet with an amount of boron commonly found in diets high in
fruits and vegetables induces changes in postmenopausal women consistent with the
prevention of calcium loss and bone demineralization.
Aged/ Aged, 80 And Over/ Boron/ Administration & Dosage/ *Pharmacology/ Calcium/
Urine/ Diet/ Estradiol/ *Blood/ Female/ Human/ Magnesium/ Urine/ Menopause/ *Metabolism/
Middle Age/ Minerals/ *Metabolism/ Phosphorus/ Urine/ Testosterone/ *Blood.
Reeves, P. G., Niesen, F. H., & Fahey, G. C. Jr. (1993)
J Nut, 123(11), 1939-1951.
For sixteen years, the American institute of Nutrition
Rodent Diets, AIN-76 and AIN-76A, have been used extensively around the world. Because of
numerous nutritional and technical problems encountered with the diet during this period,
it was revised. Two new formulations were derived: AIN-93G for growth, pregnancy and
lactation, and AIN-93m for adult maintenance. Some major differences in the new
formulation of AIN-93G compared with AIN-76A are as follows: 7 g soybean oil (0.5 g
linolenic acid)/100 g diet was substituted for 5 g corn oil/100 g diet to increase the
amount of linolenic acid;cornstarch was substituted for sucrose; the amount of phosphorus
was reduced to help eliminate the problem of kidney calcification in female rats;
L-cysteine was substituted for DL-methionine as the amino acid supplement for casein, know
to be deficient in the sulfur amino acids; manganese concentration was lowered to
one-fifth the amount in the old diet; the amounts of vitamin E, vitamin K and vitamin B-12
were increased; and molybdenum, silicon, fluoride, nickel, boron,
lithium and vanadium were added to the mineral mix. for the AIN-93M maintenance diet, the
amount of fat was lowered to 40g/kg diet from 70 g/kg diet, and the amount of casein to
140 g/kg from 200 g/kg in the AIN-93G diet. Because of a better balance of essential
nutrients, the AIN-93 diets may prove to be a better choice than AIN-76A for long-term as
well as short-term studies with laboratory rodents.
DNAL 389.8-J82.
rodents-/ feed-formulation/ nutrient-content/ energy-content/ vitamin-content/
mineral-content/ feed-mixing/ storage-/ purified diet/ nutrient requirements/ rats/ mice
experimental-diets.
Mail Order Form Click Here!
View
Shopping Cart / Checkout
